Metabolic syndrome Immunopathological processes and comorbidities

Metabolic syndrome is a systemic, and in most cases preventable, disease with a growing incidence, characterised by the combination of obesity, insulin resistance, dyslipidaemia, and hypertension. It threatens individual health and places a significant burden on the healthcare system. This publication covers the epidemiology, pathogenesis, comorbidities, and non-pharmacological treatment, with an emphasis on the role of adiposopathy and chronic inflammation. Special attention is paid to diseases associated with increased immune activity. The book provides a comprehensive perspective thanks to the collaboration of experts in metabolic syndrome, immunology, and preventive medicine from the 3rd Department of Internal Medicine – Gerontometabolism, the Institute of Clinical Immunology and Allergology of the Faculty of Medicine in Hradec Králové and University Hospital Hradec Králové, and the Institute of Preventive Medicine of the Faculty of Medicine in Hradec Králové.